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CP of toxicology
اسطمبة د/ شيرين
اللي بين قوسين دي الحاجات اللي مش بتبقى دايما موجودة يعني ساعات وساعات على حسب التوكسين
GIT
nausea, vomiting, colic, diarrhea (or constipation)
Heart
decrease BP, decrease pulse, arrest (arrythmia)
Sensory nervous system (stimulation then depression)
stinging, numbness, hypertension, hyperthermia
Motor nervous system (stimulation then depression)
twitches, respiratory muscles paralysis = peripheral asphyxia
CNS (stimulation) CHAIR
convulsions
hyperthermia & hyperreflexia
anxiety
irritability
restlessness
CNS (depression)
coma, cyanosis, respiratory center depression = central asphyxia
Liver
pain & tenderness in hypochondrium
jaundice & bleeding
increase bilirubin & enzymes
increase thrombin time
decrease albumin
Kidney
oliguria with ABC (albumin + blood + casts)
then anuria
GooD LucK
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